Why Does Lubricant Choice Matter When Trying to Conceive?



A recent study published last week in the official journal of the American Society of Reproductive Medicine, showed that Pre~Seed was the only vaginal dryness product tested that didn’t harm sperm motility as compared to Astroglide, Femglide (similar to Slippery Stuff), & Replens; or damage sperm DNA (genetic material) as compared to Femglide or KY. This data backs up over 10 other publications showing that standard lubricants and saliva, harm sperm, and should be avoided while TTC.

The reason for this comes down to pH and ion concentration or “osmolarity”. In general, the following ingredients are associated with the hyperosmotic conditions (high ion concentrations) that are damaging to sperm including: glycerol, glycerin, propylene glycol, mineral oil. In addition, glycerol itself has been shown to directly damage sperm. These ingredients should be avoided when you are trying to conceive. The hyperosmotic products not only disturb motility or swimming of the sperm, but they also cause changes in the sperm that make it hard for them to bind to the egg, even if they can still swim. Some lubricant products are actually hypo-osmotic (or have too low of an ion concentration for sperm), including Femglide & Slippery Stuff products. In some studies, low ion concentrations are actually worse for sperm than the high ion products.

Most lubricants also have pH levels that are so low they kill sperm fairly quickly. For these reasons, published medical studies have recommended in the past that NO lubricants be used while TTC. I guess it makes sense – these products were developed to decrease friction during intercourse, without any thought about sperm comfort or survival. J In contrast, as a Sperm Physiologist, I spent 10 years developing and testing the formula for Pre~Seed, specifically with sperm function in mind. Pre~Seed has the same ion concentration & pH as your body fluids, so sperm are not shocked when they encounter it. Studies done at Washington State University showed that even 50% concentrations (so half Pre~Seed) didn’t interfere with in vitro fertilization and embryo development using an animal model.

I am proud of the work we have done and continue to do on Pre~Seed, and am honored by the stories we hear from user’s like you all. I personally read each of these emails and they bless us all here! I look forward to visiting with you all next month.

Dr. E (PhD- Sperm Physiologist and Inventor of Pre~Seed)
Stay informed about Pre~Seed & related topics at Dr. E’s Blog at preseed.com


Last modified: February 10, 2013