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Conception Success Rate With Clomid

Clomid is one of the fertility medications with the highest success rates. In addition, Clomid is one of the most inexpensive of fertility treatments available. However, Clomid does not work for every patient. Because women’s bodies are so different from one another, their reactions to Clomid can also be very different. Some women do experience a variety of side effects with Clomid, while other women may not experience any.

To understand why the success rate with Clomid is so high in terms of promoting conception, it is important to understand what Clomid is and how it works. Clomid reacts with a variety of tissues in the body that have estrogen receptors, including the vagina, the cervix, the entometrium, the pituitary gland, the ovaries, and the hypothalamus. Clomid influences the way that the hormones that are related to fertility and ovulation, including GnRH, FSH, LH, and estradiol work in the body and relate to one another. It has been said that Clomid “fools” the body into believing that estrogen is low, which then causes more GnRH to be released, which spurs the production of more FSH and LH. More FSH and more LH, then, lead to the release of one or more mature eggs. This is what helps Clomid to cause ovulation, and why Clomid has such high rates of success in terms of conception.

Somewhere between 40 and 80 percent of women who take Clomid will have success in creating ovulation. This, of course, does not guarantee they will have a successful conception, however. Of those patients who successfully ovulate as a result of taking Clomid, somewhere around half of those will have a successful conception within six months. There are some other fertility medications that may have higher success rates in terms of conception, but those other medications also tend to have much higher costs than Clomid, and they tend to pose much higher risks in terms of side effects. In addition, their success rates are truly not that much higher than success rates with Clomid. For these reasons, Clomid is often prescribed instead of, or at least before, other fertility medications or procedures.

  • Pixy

    well, i am on my 6th cycle. i hope it works! been trying 2 years and without clomid i have anovulatory cycles…

  • earthsmagic

    Good luck Pixy! Do the doctors know what is causing yoru anovulatory cycles? If it is due to PCOS you might want to have a look at Pregnitude It has a pretty good record of restoring ovulation / cycles in women with PCOS. Of course, don’t take it unless you talk to your doctor about it first.

  • Aisha lovely

    i am very excited, my doctor want me to start it on my next cycle been trying to conceive for four years without Clomid. hope it works…

  • Sherrika BELLAMY

    On my 3rd dose of Clomid. Just increase to 150 mg. Hubby and I am praying this works. We can not afford IVF! Keep us in your prayers.

  • Laura

    I am about to try Clomid for the first time as well, after 4 years of zero conception. Fingers crossed… Good luck to you!


Last modified: February 10, 2013


The information provided here should not be considered medical advice. It is based on the average experience of women trying to conceive and may not be what you may be experiencing. It's not meant to be a replacement for any advice you may receive from your doctor. If you have any concerns about your cycle or our ability to get pregnant, we advise you to contact your doctor.