Clomid and Conception



If you are considering infertility treatment or have done any research regarding infertility you have undoubtedly heard about Clomid and how it has helped many women ovulate and ultimately conceive. You may be interested in learning more about Clomid and the role it plays in conception.

Of all fertility medications, Clomid has one of the highest rates of success as far as pregnancy is concerned. Another benefit is that Clomid is actually quite affordable compared to many other types of medications for infertility. This may sound like the “perfect” drug since it is effective and affordable, however it won’t work for some women. Not all women will react to Clomid in the same way, either. For example, some women will experience side effects when they take Clomid and then other women won’t experience any at all.

How it Works

Clomid works because it reacts with the parts of the body that have estrogen receptors. The drug will affect how the fertility and ovulation hormones work and react to each other. This includes the hormones FSH, LH, GRH, and estradiol. The drug makes the body believe that it has low estrogen so that more GnRH will be released and cause more LH and FSH to be produced, too. When this occurs ovulation will occur with one or more eggs. Because this drugs spurs on ovulation it is very successful in women who don’t have any other factors.





Ovulation Success

The success rate of Clomid is 40 to 80% for ovulation to occur. Simply because ovulation occurs, however, does not mean that conception will occur. Of the patients who ovulate on Clomid only half of those will actually conceive in six months. There are other drugs that have better percentages of conception than Clomid, however they are much more expensive and have more side effects than Clomid. It’s important to remember, however, that when compared side by side the results of Clomid and other drugs are not that much different and when the other considerations are compared, like cost and side effects; Clomid always comes out on top. That’s why this drug is offered to women first and will likely continue to be for some time until a better drug or conception method is developed.


Last modified: February 10, 2013